Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06WEB
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| Former ID |
DIB002288
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| Drug Name |
LAF-389
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| Synonyms |
Bengamide B, Novartis; Bengamide E, Novartis; Bengamides, Novartis; Anticancer therapy (ciclosporin derivatives), Novartis; Anticancer therapy (cyclosporin A derivatives), Novartis; Anticancer therapy (cyclosporine derivatives), Novartis
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Discontinued in Phase 1 | [1] | |
| Company |
Novartis Institutes for BioMedical Research Inc
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| Structure |
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Download2D MOL |
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| Formula |
C25H42N2O8
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| Canonical SMILES |
CC(C)(C)C=CC(C(C(C(C(=O)NC1CCC(CNC1=O)OC(=O)C2CCCCC2)OC)O)O)O
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| InChI |
1S/C25H42N2O8/c1-25(2,3)13-12-18(28)19(29)20(30)21(34-4)23(32)27-17-11-10-16(14-26-22(17)31)35-24(33)15-8-6-5-7-9-15/h12-13,15-21,28-30H,5-11,14H2,1-4H3,(H,26,31)(H,27,32)/b13-12+/t16-,17+,18-,19+,20-,21-/m1/s1
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| InChIKey |
XSYJUVKQRPLTAU-BKMGADMVSA-N
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017972) | |||
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