Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06RIM
|
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| Former ID |
DNCL002879
|
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| Drug Name |
LIM-0705
|
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| Indication | Insulin-resistant disorder [ICD-11: 5A44; ICD-10: E10-E14] | Phase 2 | [1] | |
| Company |
Limerick Biopharma
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C15H11O10P
|
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| Canonical SMILES |
C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)OP(=O)(O)O)O
|
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| InChI |
1S/C15H11O10P/c16-7-4-9(18)12-11(5-7)24-15(14(20)13(12)19)6-1-2-8(17)10(3-6)25-26(21,22)23/h1-5,16-18,20H,(H2,21,22,23)
|
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| InChIKey |
UWJBYNLLMAPJMM-UHFFFAOYSA-N
|
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| CAS Number |
CAS 1111616-69-3
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | ATP-binding cassette transporter (ABCA) | Target Info | Activator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01364155) Safety, Tolerability, PK, and PD of LIM-0705 in Subjects With Impaired Glucose Tolerance or Abnormal HOMA-IR. U.S. National Institutes of Health. | |||
| REF 2 | WO patent application no. 2010,0428,86, Pyrone analogs for therapeutic treatment. | |||
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