Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06PKS
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| Former ID |
DIB013756
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| Drug Name |
ONO-4007
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| Synonyms |
Ono-4007
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| Drug Type |
Small molecular drug
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| Indication | Immune System disease [ICD-11: 4A01-4B41] | Discontinued in Phase 2 | [1] | |
| Company |
Ono Pharmaceutical Co Ltd
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| Structure |
 |
Download2D MOL |
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| Formula |
C50H78NNaO12S
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| Canonical SMILES |
CCCCCCCCCCCC(CC(=O)NC1C(C(C(OC1O)CO)OS(=O)(=O)[O-])OC(=O)CCCCCCCCC2=CC=CC=C2)OC(=O)CCCCCCCCC3=CC=CC=C3.[Na+]
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| InChI |
1S/C50H79NO12S.Na/c1-2-3-4-5-6-7-8-15-26-35-42(60-45(54)36-27-16-11-9-13-20-29-40-31-22-18-23-32-40)38-44(53)51-47-49(48(63-64(57,58)59)43(39-52)61-50(47)56)62-46(55)37-28-17-12-10-14-21-30-41-33-24-19-25-34-41;/h18-19,22-25,31-34,42-43,47-50,52,56H,2-17,20-21,26-30,35-39H2,1H3,(H,51,53)(H,57,58,59);/q;+1/p-1/t42-,43+,47+,48+,49+,50?;/m0./s1
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| InChIKey |
KSLCVWMGAOQHEA-TZBBHZOSSA-M
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Toll-like receptor (TLR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003036) | |||
| REF 2 | Toll-like receptors TLR2 and TLR4 initiate the innate immune response of the renal tubular epithelium to bacterial products. Clin Exp Immunol. 2006 August; 145(2): 346-356. | |||
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