Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D06PJD
|
|||
Former ID |
DNC009356
|
|||
Drug Name |
3-(1H-indol-1-yl)-N-methyl-3-phenylpropan-1-amine
|
|||
Synonyms |
CHEMBL453838; SCHEMBL2074980; 3-(1H-indol-1-yl)-N-methyl-3-phenylpropan-1-amine; VDFAJYFMKVKZLC-UHFFFAOYSA-N; BDBM50245797
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C18H20N2
|
|||
Canonical SMILES |
CNCCC(C1=CC=CC=C1)N2C=CC3=CC=CC=C32
|
|||
InChI |
1S/C18H20N2/c1-19-13-11-18(15-7-3-2-4-8-15)20-14-12-16-9-5-6-10-17(16)20/h2-10,12,14,18-19H,11,13H2,1H3
|
|||
InChIKey |
VDFAJYFMKVKZLC-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Norepinephrine transporter (NET) | Target Info | Inhibitor | [1] |
Serotonin transporter (SERT) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Serotonergic synapse | |||
NetPath Pathway | TCR Signaling Pathway | |||
Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
5HT1 type receptor mediated signaling pathway | ||||
5HT2 type receptor mediated signaling pathway | ||||
5HT3 type receptor mediated signaling pathway | ||||
5HT4 type receptor mediated signaling pathway | ||||
Reactome | Na+/Cl- dependent neurotransmitter transporters | |||
WikiPathways | Monoamine Transport | |||
NRF2 pathway | ||||
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||||
SIDS Susceptibility Pathways | ||||
Synaptic Vesicle Pathway | ||||
Serotonin Transporter Activity |
References | Top | |||
---|---|---|---|---|
REF 1 | Synthesis and activity of novel 1- or 3-(3-amino-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones as selective norepinephrine reuptake inhibitors. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6067-70. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.