Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06OZW
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| Former ID |
DIB004970
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| Drug Name |
Artemisone
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| Synonyms |
Artemifone; Artemisone, Medicines For Malaria Venture; MMV-00/1007; Artemisinin derviative, Bayer/WHO/Hong Kong University; Artemisone, Bayer/WHO/Hong Kong University; Semi-synthetic endoperoxide, Bayer/WHO/Hong Kong University
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| Drug Type |
Small molecular drug
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| Indication | Malaria [ICD-11: 1F40-1F45; ICD-10: B50-B64, B54] | Phase 2/3 | [1] | |
| Company |
Hong Kong University of Science & Technology
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| Structure |
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Download2D MOL |
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| Formula |
C19H31NO6S
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| Canonical SMILES |
CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)N5CCS(=O)(=O)CC5)C
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| InChI |
1S/C19H31NO6S/c1-12-4-5-15-13(2)16(20-8-10-27(21,22)11-9-20)23-17-19(15)14(12)6-7-18(3,24-17)25-26-19/h12-17H,4-11H2,1-3H3/t12-,13-,14+,15+,16-,17-,18-,19-/m1/s1
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| InChIKey |
FDMUNKXWYMSZIR-NQWKWHCYSA-N
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| CAS Number |
CAS 255730-18-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Beta-hematin formation (BHF) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00936767) Artemisone for the Treatment of Uncomplicated Falciparum Malaria in Western Cambodia. U.S. National Institutes of Health. | |||
| REF 2 | Anticancer Properties of Distinct Antimalarial Drug Classes. PLoS One. 2013; 8(12): e82962. | |||
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