Drug Information
Drug General Information | Top | |||
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Drug ID |
D06NHW
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Former ID |
DNC002242
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Drug Name |
ISIS 222039
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Drug Type |
Antisense drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Company |
Isis Pharmaceuticals
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Target and Pathway | Top | |||
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Target(s) | HIF2-alpha messenger RNA (EPAS1 mRNA) | Target Info | . | [1] |
KEGG Pathway | Pathways in cancer | |||
Renal cell carcinoma | ||||
NetPath Pathway | TCR Signaling Pathway | |||
TGF_beta_Receptor Signaling Pathway | ||||
Pathway Interaction Database | HIF-2-alpha transcription factor network | |||
Reactome | Regulation of gene expression by Hypoxia-inducible Factor | |||
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | ||||
Transcriptional regulation of pluripotent stem cells | ||||
WikiPathways | Transcriptional regulation of pluripotent stem cells | |||
Regulation of Hypoxia-inducible Factor (HIF) by Oxygen | ||||
Adipogenesis |
References | Top | |||
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REF 1 | US patent application no. 7,217,572, Modulation of HIF1.alpha. and HIF2.alpha. expression. |
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