Drug Information
Drug General Information | Top | |||
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Drug ID |
D06LAX
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Former ID |
DIB001517
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Drug Name |
PGI-02749
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Synonyms |
PGI-02776; ZJ-11; ZJ-17; ZJ-43; NAAG peptidase inhibitors (brain injury, schizophrenia, pain); GCPII inhibitors (brain injury, schizophrenia, pain), PsychoGenics; Glutamate carboxypeptidase II inhibitors (brain injury, schizophrenia, pain), PsychoGenics; NAAG peptidase inhibitors (brain injury, schizophrenia, pain), PsychoGenics; N-acetylaspartylglutamate peptidase inhibitors (brain injury, schizophrenia, pain), PsychoGenics
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Indication | Brain injury [ICD-11: NA07.Z] | Investigative | [1] | |
Company |
Acenta Discovery
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Structure |
Download2D MOL |
Target and Pathway | Top | |||
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Target(s) | Glutamate carboxypeptidase II (GCPII) | Target Info | Inhibitor | [1] |
KEGG Pathway | Alanine, aspartate and glutamate metabolism | |||
Metabolic pathways | ||||
Vitamin digestion and absorption | ||||
NetPath Pathway | TCR Signaling Pathway | |||
TNFalpha Signaling Pathway | ||||
Reactome | Amino acid synthesis and interconversion (transamination) | |||
WikiPathways | One Carbon Metabolism |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1606). |
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