Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06JPQ
|
|||
| Former ID |
DIB019791
|
|||
| Drug Name |
DY131
|
|||
| Synonyms |
DY-131; GSK9089
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
|
||
| Formula |
C18H21N3O2
|
|||
| Canonical SMILES |
CCN(CC)C1=CC=C(C=C1)C=NNC(=O)C2=CC=C(C=C2)O
|
|||
| InChI |
1S/C18H21N3O2/c1-3-21(4-2)16-9-5-14(6-10-16)13-19-20-18(23)15-7-11-17(22)12-8-15/h5-13,22H,3-4H2,1-2H3,(H,20,23)/b19-13+
|
|||
| InChIKey |
WLKOCYWYAWBGKY-CPNJWEJPSA-N
|
|||
| CAS Number |
CAS 95167-41-2
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
11695072, 16340705, 24724493, 25277853, 26753253, 29215133, 39477425, 49846254, 51898843, 53789439, 57364833, 85787648, 91746501, 103463429, 105651049, 114008115, 130952052, 135352601, 135698126, 137615851, 162248844, 163620922, 163686243, 164758177, 172649036, 184542748, 185974887, 198967032, 227371461, 242060264, 252156398, 252365411, 252478495
|
|||
| ChEBI ID |
CHEBI:93087
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Estrogen-related receptor-beta (ESRRB) | Target Info | Agonist | [2] |
| Estrogen-related receptor-gamma (ESRRG) | Target Info | Agonist | [3] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2834). | |||
| REF 2 | Identification of an agonist ligand for estrogen-related receptors ERRbeta/gamma. Bioorg Med Chem Lett. 2005 Mar 1;15(5):1311-3. | |||
| REF 3 | Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRbeta and ERRgamma. J Med Chem. 2005 May 5;48(9):3107-9. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.