Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06JBP
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| Former ID |
DNC011519
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| Drug Name |
Benzyl-(9H-beta-carbolin-6-yl)-amine
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| Synonyms |
N-benzyl-9H-pyrido[3,4-b]indol-6-amine; NSC629813; AC1Q4YVW; AC1L7O8V; CHEMBL54968; ZINC13223121; Benzyl-(9H-; A-carbolin-6-yl)-amine; NCI60_009694; N-Benzyl-9H-beta-carbolin-6-amine hydrochloride
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H15N3
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| Canonical SMILES |
C1=CC=C(C=C1)CNC2=CC3=C(C=C2)NC4=C3C=CN=C4
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| InChI |
1S/C18H15N3/c1-2-4-13(5-3-1)11-20-14-6-7-17-16(10-14)15-8-9-19-12-18(15)21-17/h1-10,12,20-21H,11H2
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| InChIKey |
QLFFRGDGVGTTAT-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore. J Med Chem. 1988 Sep;31(9):1854-61. | |||
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