Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06IYU
|
|||
| Former ID |
DNC006644
|
|||
| Drug Name |
PHENYLSULFAMIDE
|
|||
| Synonyms |
phenylsulfamide; N-phenylsulfamide; 15959-53-2; N-phenylaminosulfonamide; aniline sulfonic acid amide; CHEMBL168514; Sulfamide, phenyl-; Sulfamide, N-phenyl-; (Sulfamoylamino)Benzene; N-Phenylsulfuric diamide; SCHEMBL253104; CTK0E6878; DTXSID50574504; DEVUYWTZRXOMSI-UHFFFAOYSA-N; MolPort-030-912-022; ZINC13488090; BDBM50124170; AKOS029900887; 79499-EP2305698A2; 79499-EP2305697A2; 79499-EP2305695A2; 79499-EP2305696A2
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C6H8N2O2S
|
|||
| Canonical SMILES |
C1=CC=C(C=C1)NS(=O)(=O)N
|
|||
| InChI |
1S/C6H8N2O2S/c7-11(9,10)8-6-4-2-1-3-5-6/h1-5,8H,(H2,7,9,10)
|
|||
| InChIKey |
DEVUYWTZRXOMSI-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 15959-53-2
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Collecting duct acid secretion | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| EGFR1 Signaling Pathway | ||||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | |||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| Reversible hydration of carbon dioxide | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Inhibition of carbonic anhydrase-II by sulfamate and sulfamide groups: an investigation involving direct thermodynamic binding measurements. J Med Chem. 2006 Jun 15;49(12):3496-500. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.