Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06IDO
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| Former ID |
DNC000706
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| Drug Name |
GS4071
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| Synonyms |
Oseltamivir acid; 187227-45-8; Oseltamivir carboxylate; Oseltamivir (acid); GS 4071; Ro 64-0802; UNII-K6106LV5Q8; CHEMBL674; CHEBI:73139; K6106LV5Q8; GS-4071; (3R,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid; 5-N-ACETYL-3-(1-ETHYLPROPYL)-1-CYCLOHEXENE-1-CARBOXYLIC ACID; 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, (3R,4R,5S)-; (3r,4r,5s)-4-(Acetylamino)-5-Amino-3-(Pentan-3-Yloxy)cyclohex-1-Ene-1-Carboxylic Acid; G39; Oseltamivir-carboxylate; 2,4-diamino triazine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2], [3] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C14H24N2O4
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| Canonical SMILES |
CCC(CC)OC1C=C(CC(C1NC(=O)C)N)C(=O)O
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| InChI |
1S/C14H24N2O4/c1-4-10(5-2)20-12-7-9(14(18)19)6-11(15)13(12)16-8(3)17/h7,10-13H,4-6,15H2,1-3H3,(H,16,17)(H,18,19)/t11-,12+,13+/m0/s1
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| InChIKey |
NENPYTRHICXVCS-YNEHKIRRSA-N
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| CAS Number |
CAS 187227-45-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
638446, 7887687, 8034633, 10300349, 12015074, 14716762, 14716763, 14716782, 14716783, 14848889, 15222406, 26717844, 26717859, 36890976, 49738106, 49738107, 53787640, 57404916, 78352940, 99289457, 104234161, 104640863, 118043620, 128690901, 134339594, 134340066, 134351728, 135228135, 137129042, 138265763, 138688175, 144242084, 144242098, 152258535, 160647369, 163304396, 163425916, 163426413, 163426425, 164763868, 165697827, 177012126, 180189081, 184528396, 185972174, 198961522, 198991424, 223704188, 226543353, 252110551
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| ChEBI ID |
CHEBI:73139
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Influenza Neuraminidase (Influ NA) | Target Info | Inhibitor | [1], [2], [3] |
| KEGG Pathway | Other glycan degradation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Antiviral agents active against influenza A viruses. Nat Rev Drug Discov. 2006 Dec;5(12):1015-25. | |||
| REF 2 | Comparison of the anti-influenza virus activity of cyclopentane derivatives with oseltamivir and zanamivir in vivo. Bioorg Med Chem. 2005 Jun 2;13(12):4071-7. | |||
| REF 3 | Syntheses and neuraminidase inhibitory activity of multisubstituted cyclopentane amide derivatives. J Med Chem. 2004 Apr 8;47(8):1919-29. | |||
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