Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06HCP
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| Former ID |
DNC013016
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| Drug Name |
MELARSOPROL
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| Synonyms |
MELARSOPROL; Mel B; Arsobal; 494-79-1; Melarsoprolum [INN-Latin]; EINECS 207-793-4; Melarsoprol [INN:BAN:DCF]; RP 3854; CHEBI:6729; [2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol; 1,3,2-Dithiarsolane-4-methanol, 2-(4-((4,6-diamino-1,3,5-triazin-2-yl)amino)phenyl)-; Melarsoprolum; Melarsenoxid-BAL; 2-(p-(4,6-Diamino-s-triazin-2-ylamino)phenyl)-1,3,2-dithiarsolane-4-methanol; C12H15AsN6OS2; Specia; UNII-ZF3786Q2E8; Melarsoprol (INN); AC1L1UXN; Mel B (TN); CHEMBL166; SCHEMBL61707; ZF3786Q2E8
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| Drug Type |
Small molecular drug
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| Indication | Trypanosomiasis [ICD-11: 1D51-1F53; ICD-10: B56-B57; ICD-9: 086.5-086] | Approved | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H15AsN6OS2
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| Canonical SMILES |
C1C(S[As](S1)C2=CC=C(C=C2)NC3=NC(=NC(=N3)N)N)CO
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| InChI |
1S/C12H15AsN6OS2/c14-10-17-11(15)19-12(18-10)16-8-3-1-7(2-4-8)13-21-6-9(5-20)22-13/h1-4,9,20H,5-6H2,(H5,14,15,16,17,18,19)
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| InChIKey |
JCYZMTMYPZHVBF-UHFFFAOYSA-N
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| CAS Number |
CAS 494-79-1
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:6729
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| SuperDrug ATC ID |
P01CD01
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cysteine protease (CYP) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | On-bead screening of a combinatorial fumaric acid derived peptide library yields antiplasmodial cysteine protease inhibitors with unusual peptide s... J Med Chem. 2009 Sep 24;52(18):5662-72. | |||
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