Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06FTI
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| Former ID |
DNC002443
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| Drug Name |
2-(1,1'-Biphenyl-4-Yl)Propanoic Acid
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| Synonyms |
alpha-Methyl-4-biphenylacetic acid; 6341-72-6; BPPA; NSC 16300; Ly 71130; 2-(p-Biphenyl)propionic acid; 2-(4-phenylphenyl)propanoic acid; 4-BIPHENYLACETIC ACID, alpha-METHYL-; CHEMBL317434; 2-Biphenyl-4-yl-propionic acid; Biprofen; 2-(4-Biphenylyl)propionic Acid; (1,1'-Biphenyl)-4-acetic acid, alpha-methyl-; 2-[1,1'-biphenyl]-4-ylpropanoic acid; [1,1'-Biphenyl]-4-aceticacid, a-methyl-; [1,1'-Biphenyl]-4-acetic acid, alpha-methyl-; alpha-Methyl-4-biphenyl-acetic acid; p-Phenylhydratropic Acid; 2-(4-Biphenyl)propionic acid,; Alpha-Methyl-4-biphenyl-acetic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H14O2
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| Canonical SMILES |
CC(C1=CC=C(C=C1)C2=CC=CC=C2)C(=O)O
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| InChI |
1S/C15H14O2/c1-11(15(16)17)12-7-9-14(10-8-12)13-5-3-2-4-6-13/h2-11H,1H3,(H,16,17)/t11-/m0/s1
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| InChIKey |
JALUUBQFLPUJMY-NSHDSACASA-N
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| CAS Number |
CAS 10532-14-6
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin G/H synthase 1 (COX-1) | Target Info | Inhibitor | [1], [2] |
| BioCyc | C20 prostanoid biosynthesis | |||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Platelet activation | ||||
| Serotonergic synapse | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| Arachidonic acid metabolism | ||||
| Phase 1 - Functionalization of compounds | ||||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | |||
| REF 2 | In silico search for multi-target anti-inflammatories in Chinese herbs and formulas. Bioorg Med Chem. 2010 Mar 15;18(6):2204-2218. | |||
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