Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06CED
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| Former ID |
DNC010812
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| Drug Name |
3'-(5-Chloro-2-thienyl)biphenyl-3-ol
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| Synonyms |
CHEMBL1097014; BDBM50318419
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H11ClOS
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| Canonical SMILES |
C1=CC(=CC(=C1)C2=CC=C(S2)Cl)C3=CC(=CC=C3)O
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| InChI |
1S/C16H11ClOS/c17-16-8-7-15(19-16)13-5-1-3-11(9-13)12-4-2-6-14(18)10-12/h1-10,18H
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| InChIKey |
IBTNRYGKAUWUJS-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Estradiol 17 beta-dehydrogenase 1 (17-beta-HSD1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Estradiol biosynthesis I | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Ovarian steroidogenesis | ||||
| NetPath Pathway | FSH Signaling Pathway | |||
| Panther Pathway | Androgen/estrogene/progesterone biosynthesis | |||
| Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
| Reactome | The canonical retinoid cycle in rods (twilight vision) | |||
| WikiPathways | Steroid Biosynthesis | |||
| Metabolism of steroid hormones and vitamin D | ||||
| Prostate Cancer | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel estrone mimetics with high 17beta-HSD1 inhibitory activity. Bioorg Med Chem. 2010 May 15;18(10):3494-505. | |||
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