Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06CDO
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| Drug Name |
Chlorphentermine Hydrochloride
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| Synonyms |
Pre-sate
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| Drug Type |
Small molecular drug
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| Indication | Appetite suppressant [ICD-11: MG43; ICD-10: R63, R63.8] | Approved | [1] | |
| Company |
Parke Davis Div Warner Lambert Co
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| Structure |
 |
Download2D MOL
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| Formula |
C10H15Cl2N
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| Canonical SMILES |
CC(C)(CC1=CC=C(C=C1)Cl)N.Cl
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| InChI |
1S/C10H14ClN.ClH/c1-10(2,12)7-8-3-5-9(11)6-4-8;/h3-6H,7,12H2,1-2H3;1H
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| InChIKey |
WEJDYJKJPUPMLH-UHFFFAOYSA-N
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| CAS Number |
CAS 151-06-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Serotonin transporter (SERT) | Target Info | Modulator | [2] |
| KEGG Pathway | Serotonergic synapse | |||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | 5HT1 type receptor mediated signaling pathway | |||
| 5HT2 type receptor mediated signaling pathway | ||||
| 5HT3 type receptor mediated signaling pathway | ||||
| 5HT4 type receptor mediated signaling pathway | ||||
| WikiPathways | Monoamine Transport | |||
| SIDS Susceptibility Pathways | ||||
| NRF2 pathway | ||||
| Synaptic Vesicle Pathway | ||||
| Serotonin Transporter Activity | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates.Implications for primary pulmonary hypertension.Circulation.1999 Aug 24;100(8):869-75. | |||
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