Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06AFP
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| Former ID |
DNC004978
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| Drug Name |
N-Hydroxy-2-(naphthalen-2-ylsulfanyl)-acetamide
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| Synonyms |
CHEMBL182879; 834918-57-9; N-Hydroxy-2-(naphthalen-2-ylsulfanyl)-acetamide; CTK3D2016; DTXSID40465831; BDBM50157325; AKOS030565680; Acetamide, N-hydroxy-2-(2-naphthalenylthio)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H11NO2S
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| Canonical SMILES |
C1=CC=C2C=C(C=CC2=C1)SCC(=O)NO
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| InChI |
1S/C12H11NO2S/c14-12(13-15)8-16-11-6-5-9-3-1-2-4-10(9)7-11/h1-7,15H,8H2,(H,13,14)
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| InChIKey |
GNDJOJQVOFQQBM-UHFFFAOYSA-N
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| CAS Number |
CAS 834918-57-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Aminopeptidase N (ANPEP) | Target Info | Inhibitor | [1] |
| BioCyc | Glutathione-mediated detoxification | |||
| KEGG Pathway | Glutathione metabolism | |||
| Metabolic pathways | ||||
| Renin-angiotensin system | ||||
| Hematopoietic cell lineage | ||||
| Pathwhiz Pathway | Glutathione Metabolism | |||
| Pathway Interaction Database | C-MYB transcription factor network | |||
| Reactome | Metabolism of Angiotensinogen to Angiotensins | |||
| WikiPathways | Metabolism of Angiotensinogen to Angiotensins | |||
| Cardiac Progenitor Differentiation | ||||
| miR-targeted genes in squamous cell - TarBase | ||||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| miR-targeted genes in leukocytes - TarBase | ||||
| Glutathione metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | N-hydroxy-2-(naphthalene-2-ylsulfanyl)-acetamide, a novel hydroxamic acid-based inhibitor of aminopeptidase N and its anti-angiogenic activity. Bioorg Med Chem Lett. 2005 Jan 3;15(1):181-3. | |||
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