Drug Information
Drug General Information | Top | |||
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Drug ID |
D05ZJC
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Former ID |
DNC005480
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Drug Name |
(3,5-Dibromo-4-butoxy-phenyl)-acetic acid
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Synonyms |
Benzeneacetic acid, 3,5-dibromo-4-butoxy-; SCHEMBL4890007; CHEMBL192490; BDBM18899; 340697-16-7; 2-(3,5-dibromo-4-butoxyphenyl)acetic acid; 3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9b
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C12H14Br2O3
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Canonical SMILES |
CCCCOC1=C(C=C(C=C1Br)CC(=O)O)Br
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InChI |
1S/C12H14Br2O3/c1-2-3-4-17-12-9(13)5-8(6-10(12)14)7-11(15)16/h5-6H,2-4,7H2,1H3,(H,15,16)
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InChIKey |
PDWWLSBHJFKDFA-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Thyroid hormone receptor beta (THRB) | Target Info | Inhibitor | [1] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Thyroid hormone signaling pathway | ||||
Pathway Interaction Database | RXR and RAR heterodimerization with other nuclear receptor | |||
Reactome | Nuclear Receptor transcription pathway | |||
WikiPathways | SIDS Susceptibility Pathways | |||
Hematopoietic Stem Cell Differentiation | ||||
Nuclear Receptors |
References | Top | |||
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REF 1 | Thyroid receptor ligands. 3. Design and synthesis of 3,5-dihalo-4-alkoxyphenylalkanoic acids as indirect antagonists of the thyroid hormone receptor. J Med Chem. 2005 May 5;48(9):3114-7. |
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