Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05XGI
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| Former ID |
DNC002682
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| Drug Name |
Meta-Tyrosine
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| Synonyms |
L-m-Tyrosine; 587-33-7; 3-HYDROXY-L-PHENYLALANINE; Meta-Tyrosine; (S)-2-amino-3-(3-hydroxyphenyl)propanoic acid; m-Tyrosine; 3-tyrosine; m-L-Tyrosine; 3-Hydroxyphenylalanine; UNII-D5YF57V4QW; 3-(m-Hydroxyphenyl)alanine; L-mTyr; (2S)-2-amino-3-(3-hydroxyphenyl)propanoic acid; L-M-TYR; D5YF57V4QW; L-Phenylalanine, 3-hydroxy-; MFCD00063059; AK-86473; L-META-TYROSINE; 3-(3-HYDROXYPHENYL)-L-ALANINE; D-3-hydroxyphenylalanine; L-PHE(3-OH)-OH; (2S)-2-azaniumyl-3-(3-hydroxyphenyl)propanoate; Tyrosine, meta-; MTY; m-Tyrosine, L-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C9H11NO3
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| Canonical SMILES |
C1=CC(=CC(=C1)O)CC(C(=O)O)N
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| InChI |
1S/C9H11NO3/c10-8(9(12)13)5-6-2-1-3-7(11)4-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1
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| InChIKey |
JZKXXXDKRQWDET-QMMMGPOBSA-N
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| CAS Number |
CAS 587-33-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
15066944, 23950934, 29199762, 46505633, 46507251, 49600645, 53796165, 76487857, 84975188, 84975189, 91139890, 92298673, 99373150, 114806774, 126650949, 126694755, 128349805, 131542276, 134976171, 135696480, 137009826, 140422639, 148149568, 152223927, 160813727, 160965582, 162138927, 162498447, 163373419, 163781062, 164032803, 164174587, 164204437, 165235752, 170505752, 172088320, 186003560, 196112208, 198956603, 198973834, 203095539, 204429584, 204429585, 223380698, 223530374, 224914533, 226513083, 241100312, 249840828, 250208054
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| ChEBI ID |
CHEBI:44303
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosine 3-monooxygenase (TH) | Target Info | Inhibitor | [1] |
| BioCyc | Catecholamine biosynthesis | |||
| KEGG Pathway | Tyrosine metabolism | |||
| Metabolic pathways | ||||
| Dopaminergic synapse | ||||
| Prolactin signaling pathway | ||||
| Parkinson's disease | ||||
| Cocaine addiction | ||||
| Amphetamine addiction | ||||
| Alcoholism | ||||
| Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
| Parkinson disease | ||||
| Dopamine receptor mediated signaling pathway | ||||
| Nicotine pharmacodynamics pathway | ||||
| Pathwhiz Pathway | Catecholamine Biosynthesis | |||
| Pathway Interaction Database | ATF-2 transcription factor network | |||
| AP-1 transcription factor network | ||||
| p38 signaling mediated by MAPKAP kinases | ||||
| Alpha-synuclein signaling | ||||
| WikiPathways | Monoamine Transport | |||
| SIDS Susceptibility Pathways | ||||
| Biogenic Amine Synthesis | ||||
| Dopaminergic Neurogenesis | ||||
| Metabolism of amino acids and derivatives | ||||
| Dopamine metabolism | ||||
| Parkinsons Disease Pathway | ||||
| Nicotine Activity on Dopaminergic Neurons | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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