Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05UAO
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| Former ID |
DIB016538
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| Drug Name |
J591-Ac-225
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| Synonyms |
PSMA-targeting mAb and Ac-225 conjugate (metastatic prostate cancer), Actinium Pharmaceuticals
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| Drug Type |
Antibody
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| Indication | Prostate cancer [ICD-11: 2C82.0; ICD-10: C61; ICD-9: 185] | Investigative | [1] | |
| Company |
Actinium Pharmaceuticals Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate carboxypeptidase II (GCPII) | Target Info | . | [1] |
| KEGG Pathway | Alanine, aspartate and glutamate metabolism | |||
| Metabolic pathways | ||||
| Vitamin digestion and absorption | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| TNFalpha Signaling Pathway | ||||
| Reactome | Amino acid synthesis and interconversion (transamination) | |||
| WikiPathways | One Carbon Metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1606). | |||
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