Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05TLP
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| Former ID |
DIB004288
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| Drug Name |
Carabersat
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| Synonyms |
SB-204268; SB-204269; SB-258339
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| Drug Type |
Small molecular drug
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| Indication | Epileptic seizures [ICD-11: 8A61-8A6Z; ICD-9: 345.9, 780.3] | Phase 2 | [1] | |
| Company |
SmithKline Beecham plc
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| Structure |
 |
Download2D MOL |
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| Formula |
C20H20FNO4
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| Canonical SMILES |
CC(=O)C1=CC2=C(C=C1)OC(C(C2NC(=O)C3=CC=C(C=C3)F)O)(C)C
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| InChI |
1S/C20H20FNO4/c1-11(23)13-6-9-16-15(10-13)17(18(24)20(2,3)26-16)22-19(25)12-4-7-14(21)8-5-12/h4-10,17-18,24H,1-3H3,(H,22,25)/t17-,18+/m0/s1
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| InChIKey |
RCLXAPJEFHPYEG-ZWKOTPCHSA-N
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| CAS Number |
CAS 184653-84-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Trigeminal ganglion stimulation-induced response (TGSR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | SB-204269 SmithKline Beecham. IDrugs. 1998 Sep;1(5):595-8. | |||
| REF 2 | Tonabersat (SB-220453) a novel benzopyran with anticonvulsant properties attenuates trigeminal nerve-induced neurovascular reflexes. Br J Pharmacol. 2001 April; 132(7): 1549-1557. | |||
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