Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05SZP
|
|||
| Former ID |
DNC005267
|
|||
| Drug Name |
WR-080539
|
|||
| Synonyms |
4'-Acetamidochalcone; CCRIS 2216; NSC 40307; WR-080539; CHEMBL187926; 19337-19-0; N-{4-[(2E)-3-phenylprop-2-enoyl]phenyl}acetamide; AC1NS7QX; N-(4-cinnamoylphenyl)acetamide; MolPort-018-573-532; NSC40307; ZINC4612934; STL426808; BBL035434; NSC-40307; BDBM50154614; AKOS003620252; N-[4-(trans-Cinnamoyl)phenyl]acetamide; LS-188491; N-[4-(3-Phenyl-acryloyl)-phenyl]-acetamide
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C17H15NO2
|
|||
| Canonical SMILES |
CC(=O)NC1=CC=C(C=C1)C(=O)C=CC2=CC=CC=C2
|
|||
| InChI |
1S/C17H15NO2/c1-13(19)18-16-10-8-15(9-11-16)17(20)12-7-14-5-3-2-4-6-14/h2-12H,1H3,(H,18,19)/b12-7+
|
|||
| InChIKey |
CUYJTAUCYGHYLW-KPKJPENVSA-N
|
|||
| CAS Number |
CAS 19337-19-0
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium CDK Pfmrk (Malaria Pfmrk) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Selective inhibition of Pfmrk, a Plasmodium falciparum CDK, by antimalarial 1,3-diaryl-2-propenones. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1982-5. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.