Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05SBR
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| Drug Name |
Piclidenoson
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| Synonyms |
IB-MECA; 152918-18-8; piclidenoson; CF-101; 3-IB-Meca; N(6)-Ibamu; CF 101; Cf101; UNII-30679UMI0N; CHEMBL119709; CHEBI:73286; 30679UMI0N; RPR-113090; IB-Meca
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| Drug Type |
Small molecular drug
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| Indication | Keratoconjunctivitis sicca [ICD-11: 9A79] | Phase 3 | [1] | |
| Coronavirus Disease 2019 (COVID-19) [ICD-11: 1D6Y] | Phase 2 | [2] | ||
| Therapeutic Class |
Antiviral Agents
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| Structure |
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Download2D MOL |
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| Formula |
C18H19IN6O4
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| Canonical SMILES |
CNC(=O)C1C(C(C(O1)N2C=NC3=C(N=CN=C32)NCC4=CC(=CC=C4)I)O)O
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| InChI |
1S/C18H19IN6O4/c1-20-17(28)14-12(26)13(27)18(29-14)25-8-24-11-15(22-7-23-16(11)25)21-6-9-3-2-4-10(19)5-9/h2-5,7-8,12-14,18,26-27H,6H2,1H3,(H,20,28)(H,21,22,23)/t12-,13+,14-,18+/m0/s1
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| InChIKey |
HUJXGQILHAUCCV-MOROJQBDSA-N
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| CAS Number |
CAS 152918-18-8
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:73286
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01235234) Trial of CF101 to Treat Patients With Dry Eye Disease. U.S. National Institutes of Health. | |||
| REF 2 | ClinicalTrials.gov (NCT04333472) Piclidenoson for Treatment of COVID-19. U.S. National Institutes of Health. | |||
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