Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05QUG
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| Former ID |
DNC010065
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| Drug Name |
7-phenethoxy-2H-chromen-2-one
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| Synonyms |
CHEMBL567544; 7-phenethoxy-2H-chromen-2-one
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|
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C17H14O2
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| Canonical SMILES |
C1=CC=C(C=C1)CCC2=CC3=C(C=C2)C=CC(=O)O3
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| InChI |
1S/C17H14O2/c18-17-11-10-15-9-8-14(12-16(15)19-17)7-6-13-4-2-1-3-5-13/h1-5,8-12H,6-7H2
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| InChIKey |
FQWWPSNGCTYUHH-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase (CA) | Target Info | Inhibitor | [1] |
| Carbonic anhydrase IX (CA-IX) | Target Info | Inhibitor | [1] | |
| Carbonic anhydrase XII (CA-XII) | Target Info | Inhibitor | [1] | |
| Carbonic anhydrase XIV (CA-XIV) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Nitrogen metabolism | |||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| Pathway Interaction Database | HIF-1-alpha transcription factor network | |||
| Reactome | Reversible hydration of carbon dioxide | |||
| Regulation of gene expression by Hypoxia-inducible Factor | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in leukocytes - TarBase | ||||
| miR-targeted genes in epithelium - TarBase | ||||
| Vitamin D Receptor Pathway | ||||
| Regulation of Hypoxia-inducible Factor (HIF) by Oxygen | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins. J Med Chem. 2010 Jan 14;53(1):335-44. | |||
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