Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05PJJ
|
|||
| Former ID |
DNC001602
|
|||
| Drug Name |
NOX 2137a/b
|
|||
| Drug Type |
Aptamer
|
|||
| Indication | Pain [ICD-11: MG30-MG3Z] | Investigative | [1] | |
| Stress [ICD-11: 6B40-6B45] | Investigative | [1] | ||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nociceptin receptor (OPRL1) | Target Info | . | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Therapeutic applications of aptamers. Expert Opin Investig Drugs. 2008 Jan;17(1):43-60. | |||
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