Drug Information
Drug General Information | Top | |||
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Drug ID |
D05MJO
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Former ID |
DNC012145
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Drug Name |
2-(3-Methyl-piperazin-1-yl)-6-nitro-quinoline
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Synonyms |
CHEMBL43526; 2-(3-Methyl-piperazin-1-yl)-6-nitro-quinoline; Quinoline,2-(3-methyl-1-piperazinyl)-6-nitro-; SCHEMBL6365197; WIRIBEHWECMIRC-UHFFFAOYSA-N; BDBM50090211; AKOS011768382; 2-(3-Methylpiperazino)-6-nitroquinoline; 296759-20-1
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C14H16N4O2
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Canonical SMILES |
CC1CN(CCN1)C2=NC3=C(C=C2)C=C(C=C3)[N+](=O)[O-]
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InChI |
1S/C14H16N4O2/c1-10-9-17(7-6-15-10)14-5-2-11-8-12(18(19)20)3-4-13(11)16-14/h2-5,8,10,15H,6-7,9H2,1H3
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InChIKey |
WIRIBEHWECMIRC-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Serotonin transporter (SERT) | Target Info | Inhibitor | [1] |
KEGG Pathway | Serotonergic synapse | |||
NetPath Pathway | TCR Signaling Pathway | |||
Panther Pathway | 5HT1 type receptor mediated signaling pathway | |||
5HT2 type receptor mediated signaling pathway | ||||
5HT3 type receptor mediated signaling pathway | ||||
5HT4 type receptor mediated signaling pathway | ||||
WikiPathways | Monoamine Transport | |||
SIDS Susceptibility Pathways | ||||
NRF2 pathway | ||||
Synaptic Vesicle Pathway | ||||
Serotonin Transporter Activity |
References | Top | |||
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REF 1 | Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 1. Bioorg Med Chem Lett. 2000 Jul 17;10(14):1559-62. |
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