Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D05LXP
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| Former ID |
DNC012319
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| Drug Name |
7,12-Dihydro-7,12-diaza-indeno[1,2-a]fluorene
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| Synonyms |
5,12-Dihydroindolo[3,2-a]carbazole; 111296-91-4; 5,12-dihydroindolo[3,2-c]carbazole; Indolo[3,2-]arbazole, 5,12-ihydro-; Indolo[3,2-a]carbazole, 5,12-dihydro-; 5H,12H-Indolo[3,2-a]carbazole; AC1NFSZ0; SCHEMBL224017; CHEMBL53230; DTXSID80405771; QQWXDAWSMPLECU-UHFFFAOYSA-N; MolPort-027-835-190; ZINC13490703; 2059AA; AKOS016009131; 5,12-dihydro-indolo[3,2-a]carbazole; Indolo[3,2-a]carbazole,5,12-dihydro-; SC-48298; AJ-63955; AX8227529
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H12N2
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| Canonical SMILES |
C1=CC=C2C(=C1)C3=C(N2)C4=C(C=C3)NC5=CC=CC=C54
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| InChI |
1S/C18H12N2/c1-3-7-14-11(5-1)12-9-10-16-17(18(12)20-14)13-6-2-4-8-15(13)19-16/h1-10,19-20H
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| InChIKey |
QQWXDAWSMPLECU-UHFFFAOYSA-N
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| CAS Number |
CAS 111296-91-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore. J Med Chem. 1988 Sep;31(9):1854-61. | |||
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