Drug Information
Drug General Information | Top | |||
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Drug ID |
D05ILO
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Former ID |
DNC013323
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Drug Name |
(R)-N2-{4-[(3-chlorobenzyl)oxy]benzyl}serinamide
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Synonyms |
CHEMBL244771; (R)-N2-{4-[(3-chlorobenzyl)oxy]benzyl}serinamide; SCHEMBL2017087
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C17H19ClN2O3
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Canonical SMILES |
C1=CC(=CC(=C1)Cl)COC2=CC=C(C=C2)CNC(CO)C(=O)N
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InChI |
1S/C17H19ClN2O3/c18-14-3-1-2-13(8-14)11-23-15-6-4-12(5-7-15)9-20-16(10-21)17(19)22/h1-8,16,20-21H,9-11H2,(H2,19,22)/t16-/m1/s1
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InChIKey |
WYDCYPPIJUASJE-MRXNPFEDSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Monoamine oxidase type B (MAO-B) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of tryptophan utilization | |||
Tryptophan degradation via tryptamine | ||||
Dopamine degradation | ||||
Putrescine degradation III | ||||
Noradrenaline and adrenaline degradation | ||||
KEGG Pathway | Glycine, serine and threonine metabolism | |||
Arginine and proline metabolism | ||||
Histidine metabolism | ||||
Tyrosine metabolism | ||||
Phenylalanine metabolism | ||||
Tryptophan metabolism | ||||
Drug metabolism - cytochrome P450 | ||||
Metabolic pathways | ||||
Serotonergic synapse | ||||
Dopaminergic synapse | ||||
Cocaine addiction | ||||
Amphetamine addiction | ||||
Alcoholism | ||||
Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
5-Hydroxytryptamine degredation | ||||
Dopamine receptor mediated signaling pathway | ||||
Pathway Interaction Database | Alpha-synuclein signaling | |||
WikiPathways | Tryptophan metabolism | |||
Dopamine metabolism | ||||
Phase 1 - Functionalization of compounds |
References | Top | |||
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REF 1 | Solid-phase synthesis and insights into structure-activity relationships of safinamide analogues as potent and selective inhibitors of type B monoa... J Med Chem. 2007 Oct 4;50(20):4909-16. |
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