Drug Information
Drug General Information | Top | |||
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Drug ID |
D05ICT
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Drug Name |
ABBV-744
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Synonyms |
OEDSFMUSNZDJFD-UHFFFAOYSA-N; 2138861-99-9; N-ethyl-4-(2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide; ABBV 744; SCHEMBL19463409; EX-A2713; ACN-054460; HY-112090; CS-0043318
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Indication | Acute myeloid leukaemia [ICD-11: 2A60] | Phase 1 | [1] | |
Prostate cancer [ICD-11: 2C82.0; ICD-9: 185] | Phase 1 | [1] | ||
Company |
AbbVieNorth Chicago, IL
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Structure |
Download2D MOL |
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Formula |
C28H30FN3O4
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Canonical SMILES |
CCNC(=O)C1=CC2=C(N1)C(=O)N(C=C2C3=C(C=CC(=C3)C(C)(C)O)OC4=C(C=C(C=C4C)F)C)C
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InChI |
1S/C28H30FN3O4/c1-7-30-26(33)22-13-20-21(14-32(6)27(34)24(20)31-22)19-12-17(28(4,5)35)8-9-23(19)36-25-15(2)10-18(29)11-16(25)3/h8-14,31,35H,7H2,1-6H3,(H,30,33)
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InChIKey |
OEDSFMUSNZDJFD-UHFFFAOYSA-N
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CAS Number |
CAS 2138861-99-9
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Bromodomain-containing protein 2 (BRD2) | Target Info | Inhibitor | [1] |
Bromodomain-containing protein 3 (BRD3) | Target Info | Inhibitor | [1] | |
Bromodomain-containing protein 4 (BRD4) | Target Info | Inhibitor | [1] | |
NetPath Pathway | IL2 Signaling Pathway | |||
TGF_beta_Receptor Signaling Pathway | ||||
Pathway Interaction Database | Regulation of retinoblastoma protein | |||
WikiPathways | Chemical Compounds to monitor Proteins |
References | Top | |||
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REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) |
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