Drug Information
Drug General Information | Top | |||
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Drug ID |
D05HBM
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Drug Name |
Benzenamine derivative 2
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Synonyms |
PMID27019002-Compound-35
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Drug Type |
Small molecular drug
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Company |
THE JOHNS HOPKINS UNIVERSITY CASERO, Robert, A. BYTHEWAY, Ian WOSTER, Patrick, M
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Structure |
Target and Pathway | Top | |||
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Target(s) | Lysine-specific histone demethylase 1 (LSD) | Target Info | Inhibitor | [1] |
Target's Patent Info | Lysine-specific histone demethylase 1 (LSD) | Target's Patent Info | [1] | |
Pathway Interaction Database | Notch signaling pathway | |||
Coregulation of Androgen receptor activity | ||||
Notch-mediated HES/HEY network | ||||
Reactome | HDACs deacetylate histones | |||
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 | ||||
Factors involved in megakaryocyte development and platelet production | ||||
WikiPathways | Factors involved in megakaryocyte development and platelet production | |||
Androgen receptor signaling pathway |
References | Top | |||
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REF 1 | LSD1 inhibitors: a patent review (2010-2015).Expert Opin Ther Pat. 2016 May;26(5):565-80. |
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