Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05GVL
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| Former ID |
DNC005050
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| Drug Name |
2-(6-Methoxy-indole-1-sulfonyl)-benzoic acid
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| Synonyms |
CHEMBL365508; 2-(6-Methoxy-indole-1-sulfonyl)-benzoic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H13NO5S
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| Canonical SMILES |
COC1=CC2=C(C=C1)C=CN2S(=O)(=O)C3=CC=CC=C3C(=O)O
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| InChI |
1S/C16H13NO5S/c1-22-12-7-6-11-8-9-17(14(11)10-12)23(20,21)15-5-3-2-4-13(15)16(18)19/h2-10H,1H3,(H,18,19)
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| InChIKey |
HQQRNJVZOJLXOO-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fatty acid-binding protein 4 (FABP4) | Target Info | Inhibitor | [1] |
| KEGG Pathway | PPAR signaling pathway | |||
| NetPath Pathway | TCR Signaling Pathway | |||
| Pathway Interaction Database | AP-1 transcription factor network | |||
| Reactome | Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | |||
| Transcriptional regulation of white adipocyte differentiation | ||||
| WikiPathways | Lipid digestion, mobilization, and transport | |||
| Transcriptional Regulation of White Adipocyte Differentiation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target. Bioorg Med Chem Lett. 2004 Sep 6;14(17):4445-8. | |||
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