Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05GPF
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| Drug Name |
US9650366, 12
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| Synonyms |
SCHEMBL17669987; BDBM308061; US9650366, 12
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| Drug Type |
Small molecular drug
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| Structure |
 |
Download2D MOL |
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| Formula |
C25H19F4N7O2
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| Canonical SMILES |
C1=CC(=CC=C1C#CC2=CC(=CN=C2)C3=NN(N=N3)CCCO)NC(=O)NC4=C(C=CC(=C4)C(F)(F)F)F
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| InChI |
1S/C25H19F4N7O2/c26-21-9-6-19(25(27,28)29)13-22(21)32-24(38)31-20-7-4-16(5-8-20)2-3-17-12-18(15-30-14-17)23-33-35-36(34-23)10-1-11-37/h4-9,12-15,37H,1,10-11H2,(H2,31,32,38)
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| InChIKey |
LOBSULBGQKFHGX-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosine-protein kinase EIF2AK2 (p68) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Tyrosine-protein kinase EIF2AK2 (p68) | Target's Patent Info | [1] | |
| Panther Pathway | Apoptosis signaling pathway | |||
| Pathway Interaction Database | Signaling events mediated by TCPTP | |||
| Ceramide signaling pathway | ||||
| PDGFR-beta signaling pathway | ||||
| Reactome | ISG15 antiviral mechanism | |||
| WikiPathways | Type II interferon signaling (IFNG) | |||
| Host Interactions with Influenza Factors | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| Translation Factors | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Heterocycle-substituted pyridyl benzothiophenes as kinase inhibitors. US9650366. | |||
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