Drug Information
Drug General Information | Top | |||
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Drug ID |
D05FKE
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Former ID |
DNC010254
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Drug Name |
6-(piperazin-1-yl)-9-propyl-9H-purine
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Synonyms |
CHEMBL594489; 6-(piperazin-1-yl)-9-propyl-9H-purine
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C12H18N6
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Canonical SMILES |
CCCN1C=NC2=C1N=CN=C2N3CCNCC3
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InChI |
1S/C12H18N6/c1-2-5-18-9-16-10-11(14-8-15-12(10)18)17-6-3-13-4-7-17/h8-9,13H,2-7H2,1H3
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InChIKey |
BWJIAIMMFVYUQA-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | 5-HT 2C receptor (HTR2C) | Target Info | Inhibitor | [1] |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Gap junction | ||||
Serotonergic synapse | ||||
Inflammatory mediator regulation of TRP channels | ||||
Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
Reactome | Serotonin receptors | |||
G alpha (q) signalling events | ||||
WikiPathways | Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Design and synthesis of orally-active and selective azaindane 5HT2c agonist for the treatment of obesity. Bioorg Med Chem Lett. 2010 Jan 1;20(1):266-71. |
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