Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05BIJ
|
|||
| Former ID |
DNC001242
|
|||
| Drug Name |
RWJ-140998
|
|||
| Synonyms |
4-hydroxy-1-methyl-7,8,9,10-tetrahydro-6H-[1,3]thiazocino[2,3-f]purin-2(1H)-one; RWJ-140998; AC1LIVUI; Oprea1_483450; MolPort-005-971-769; MolPort-002-544-111; ZINC496244; STK643127; AKOS005574570; AKOS030506897; MCULE-9461774198; 1-methyl-7,8,9,10-tetrahydro-6H-purino[8,7-b][1,3]thiazocine-2,4-dione; 1-methyl-7,8,9,10-tetrahydro-1H-[1,3]thiazocino[2,3-f]purine-2,4(3H,6H)-dione
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Gram-positive bacterial infection [ICD-11: 1B74-1G40] | Investigative | [1] | |
| Company |
DuPont, Vicuron RW Johnson
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C11H14N4O2S
|
|||
| Canonical SMILES |
CN1C2=C(C(=O)NC1=O)N3CCCCCSC3=N2
|
|||
| InChI |
1S/C11H14N4O2S/c1-14-8-7(9(16)13-10(14)17)15-5-3-2-4-6-18-11(15)12-8/h2-6H2,1H3,(H,13,16,17)
|
|||
| InChIKey |
IGKRUASVZKVVLL-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial UDP-N-acetylglucosamine carboxyvinyltransferase (Bact murA) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs for bacterial urinary tract infections. Expert Opin Emerg Drugs. 2005 May;10(2):275-98. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.