Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D05AEG
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| Former ID |
DNC011385
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| Drug Name |
N-(9H-beta-Carbolin-3-yl)-acetamide
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| Synonyms |
91985-75-0; N-9h-pyrido[3,4-b]indol-3-yl-acetamide; 3-acetamino-beta-carboline; CHEMBL167732; SCHEMBL10645219; ZINC25307; JZIFOHJMLBAWQZ-UHFFFAOYSA-N; N-(beta-Carboline-3-yl)acetamide; N-(9H-pyrido[3,4-b]indol-3-yl)acetamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H11N3O
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| Canonical SMILES |
CC(=O)NC1=NC=C2C(=C1)C3=CC=CC=C3N2
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| InChI |
1S/C13H11N3O/c1-8(17)15-13-6-10-9-4-2-3-5-11(9)16-12(10)7-14-13/h2-7,16H,1H3,(H,14,15,17)
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| InChIKey |
JZIFOHJMLBAWQZ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 3-Amino-beta-carboline derivatives and the benzodiazepine receptor. Synthesis of a selective antagonist of the sedative action of diazepam. J Med Chem. 1985 Jun;28(6):824-8. | |||
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