Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04ZTY
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| Former ID |
DAP001104
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| Drug Name |
Voglibose
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| Synonyms |
Basen; Glustat; Vocarb; Basen OD; A-71100; AO-128; Basen (TN); Basen (Takeda Chemical Industries); Volix (Ranbaxy labs);Voglibose (JP15/USAN/INN); N-(1,3-Dihydroxyprop-2-yl)valiolamine; (1S,2S,3R,4S,5S)-5-(1,3-dihydroxypropan-2-ylamino)-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol; (1S,2S,3R,4S,5S)-5-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino}-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol; 3,4-Dideoxy-4-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-D-epi-inositol
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| Drug Type |
Small molecular drug
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| Indication | Diabetic complication [ICD-11: 5A2Y; ICD-9: 253.5, 588.1] | Approved | [1] | |
| Therapeutic Class |
Hypoglycemic Agents
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| Company |
Takeda
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| Structure |
 |
Download2D MOL |
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| Formula |
C10H21NO7
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| Canonical SMILES |
C1C(C(C(C(C1(CO)O)O)O)O)NC(CO)CO
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| InChI |
1S/C10H21NO7/c12-2-5(3-13)11-6-1-10(18,4-14)9(17)8(16)7(6)15/h5-9,11-18H,1-4H2/t6-,7-,8+,9-,10-/m0/s1
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| InChIKey |
FZNCGRZWXLXZSZ-CIQUZCHMSA-N
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| CAS Number |
CAS 83480-29-9
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7848728, 10299466, 12013776, 15070756, 36887136, 46504462, 48414634, 49835305, 57404590, 80611090, 103624146, 104111539, 104631150, 119525753, 121264490, 126592896, 134223911, 134338349, 135027174, 135812317, 136367734, 136948052, 137002784, 139694698, 144205773, 152090258, 152344538, 160967826, 164178111, 164814716, 170465993, 179151268, 184545240, 198946321, 210279172, 210281495, 226397450, 241164518, 249726430, 251915707, 251917057, 252157387, 252216589, 252359063, 252451111
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| ChEBI ID |
CHEBI:32300
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| SuperDrug ATC ID |
A10BF03
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| SuperDrug CAS ID |
cas=083480299
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Intestinal maltase-glucoamylase (MGAM) | Target Info | Inhibitor | [2] |
| KEGG Pathway | Galactose metabolism | |||
| Starch and sucrose metabolism | ||||
| Metabolic pathways | ||||
| Carbohydrate digestion and absorption | ||||
| Pathwhiz Pathway | Starch and Sucrose Metabolism | |||
| WikiPathways | Metabolism of carbohydrates | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. | |||
| REF 2 | Effects of changeover from voglibose to acarbose on postprandial triglycerides in type 2 diabetes mellitus patients. Adv Ther. 2009 Jun;26(6):660-6. | |||
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