Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04ZAO
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| Former ID |
DNC003484
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| Drug Name |
7-Hydroxy-Pyrazolo[4,3-D]Pyrimidine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C5H4N4O
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| Canonical SMILES |
C1=NNC2=C1N=CNC2=O
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| InChI |
1S/C5H4N4O/c10-5-4-3(1-8-9-4)6-2-7-5/h1-2H,(H,8,9)(H,6,7,10)
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| InChIKey |
JFZSDNLQDTYVEE-UHFFFAOYSA-N
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| CAS Number |
CAS 13877-55-9
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| PubChem Compound ID | ||||
| PubChem Substance ID |
119349, 822278, 822282, 822298, 822302, 829873, 832891, 836928, 5907678, 7847291, 7885498, 29176849, 44415453, 46393216, 46504753, 57333676, 80728753, 91848212, 91849367, 103119011, 104384174, 117596228, 125751824, 126426323, 128269560, 132634693, 134413788, 135040135, 135681519, 136370681, 137013845, 137184930, 137188920, 138308461, 142444387, 144186955, 152059255, 152198570, 160821636, 160966181, 162151595, 162190561, 162514805, 163091633, 163143901, 164787716, 172093579, 172898426, 174482266, 174551392
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Hypoxanthine-guanine phosphoribosyltransferase (Malaria LACZ) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Purine metabolism | |||
| Drug metabolism - other enzymes | ||||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Purine Metabolism | |||
| Reactome | Purine salvage | |||
| WikiPathways | Nucleotide Metabolism | |||
| Mesodermal Commitment Pathway | ||||
| Endoderm Differentiation | ||||
| Metabolism of nucleotides | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41. | |||
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