Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04UTH
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| Former ID |
DIB005808
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| Drug Name |
Long-acting erythropoietin conjugate
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| Synonyms |
HM-10760; HM-10760A; LAPS-EPO; Long-acting erythropoietin conjugate (LAPS, anemia); Long-acting erythropoietin conjugate (LAPS, anemia), Hanmi
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| Indication | Anemia [ICD-11: 3A00-3A9Z; ICD-9: 280-285] | Phase 1 | [1] | |
| Company |
Hanmi pharmaceutical
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Erythropoietin (EPO) | Target Info | Modulator | [2] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| HIF-1 signaling pathway | ||||
| PI3K-Akt signaling pathway | ||||
| Jak-STAT signaling pathway | ||||
| Hematopoietic cell lineage | ||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | |||
| Signaling events mediated by Stem cell factor receptor (c-Kit) | ||||
| EPO signaling pathway | ||||
| HIF-1-alpha transcription factor network | ||||
| Reactome | Regulation of gene expression by Hypoxia-inducible Factor | |||
| WikiPathways | EPO Receptor Signaling | |||
| Hematopoietic Stem Cell Differentiation | ||||
| Differentiation Pathway | ||||
| Regulation of Hypoxia-inducible Factor (HIF) by Oxygen | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01030315) A Study of HM10760A (Long-acting Erythropoietin) in Healthy Adult Caucasian and Japanese Subjects. U.S. National Institutes of Health. | |||
| REF 2 | Company report (Pharmexcil) | |||
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