Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04TSO
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| Former ID |
DIB002751
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| Drug Name |
UNBS-1450
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| Synonyms |
UNBS-1244; Na+ K+ ATPase inhibitor, (intravenous, cancer), Unibioscreen; 2''-oxovoruscharin
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Phase 1 | [1] | |
| Company |
Unibioscreen SA
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| Structure |
 |
Download2D MOL |
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| Formula |
C31H43NO9S
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| Canonical SMILES |
CC1CC2(C3(C(O1)OC4CC5CCC6C(C5(CC4O3)CO)CCC7(C6(CCC7C8=CC(=O)OC8)O)C)O)NC(=O)CS2
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| InChI |
1S/C31H43NO9S/c1-16-11-30(32-24(34)14-42-30)31(37)26(39-16)40-22-10-18-3-4-21-20(28(18,15-33)12-23(22)41-31)5-7-27(2)19(6-8-29(21,27)36)17-9-25(35)38-13-17/h9,16,18-23,26,33,36-37H,3-8,10-15H2,1-2H3,(H,32,34)/t16-,18+,19-,20+,21-,22+,23+,26+,27-,28-,29+,30+,31-/m1/s1
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| InChIKey |
GRINEMOQBRCRRY-OVGHKGCDSA-N
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029692) | |||
| REF 2 | Early downregulation of Mcl-1 regulates apoptosis triggered by cardiac glycoside UNBS1450. Cell Death Dis. 2015 Jun 11;6:e1782. | |||
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