Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D04SFH
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| Former ID |
DAP001048
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| Drug Name |
Medrysone
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| Synonyms |
Hydroxymesterone; Medrifar; Medritonic; Medrocort; Visudrisone; Medrysone (USAN); U-8471; (6S,8S,9S,10R,11S,13S,14S,17S)-17-acetyl-11-hydroxy-6,10,13-trimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one; 11.beta.-Hydroxy-6.alpha.-methylpregn-4-ene-3,20-dione; 11.beta.-Hydroxy-6.alpha.-methylprogesterone; 11beta-Hydroxy-6alpha-methyl-4-pregnene-3,20-dione; 11beta-Hydroxy-6alpha-methylpregn-4-ene-3,20-dione; 6.alpha.-Methyl-11.beta.-hydroxyprogesterone
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| Drug Type |
Small molecular drug
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| Indication | Eye inflammation [ICD-11: 9A02; ICD-10: H00-H59; ICD-9: 360-379] | Approved | [1], [2] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C22H32O3
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| Canonical SMILES |
CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)CC4)C)O)C)C(=O)C
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| InChI |
1S/C22H32O3/c1-12-9-15-17-6-5-16(13(2)23)22(17,4)11-19(25)20(15)21(3)8-7-14(24)10-18(12)21/h10,12,15-17,19-20,25H,5-9,11H2,1-4H3/t12-,15-,16+,17-,19-,20+,21-,22+/m0/s1
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| InChIKey |
GZENKSODFLBBHQ-ILSZZQPISA-N
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| CAS Number |
CAS 2668-66-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
109976, 7849348, 7979880, 9395740, 10321190, 11466771, 11467891, 11486401, 11533031, 14827409, 17395643, 24896551, 30046333, 46506584, 47276848, 47425535, 47500776, 47647746, 48020242, 48170674, 49698627, 50124175, 50322454, 56423131, 57400476, 71825554, 85148347, 85788382, 89850274, 92125692, 95613570, 103771156, 103913670, 104170097, 104493518, 121362376, 121363363, 124583836, 124800109, 128027553, 134338310, 134983239, 137001649, 144204077, 160963601, 170465194, 172080722, 175266363, 175611984, 178103664
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| ChEBI ID |
CHEBI:34829
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| ADReCS Drug ID | BADD_D01367 | |||
| SuperDrug ATC ID |
S01BA08
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| SuperDrug CAS ID |
cas=002668668
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid hormone receptor ERR (ESRR) | Target Info | Modulator | [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7086). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 016624. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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