Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D04OPE
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| Former ID |
DIB020938
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| Drug Name |
SF-11
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| Synonyms |
TCMDC-124500; MLS001111122; SMR000457056; 3-(4-chlorophenyl)-5-methyl-4-[2-(4-methylphenyl)sulfonylpyrazol-3-yl]-1,2-oxazole; 3-(4-chlorophenyl)-5-methyl-4-{1-[(4-methylphenyl)sulfonyl]-1H-pyrazol-5-yl}isoxazole; SR-01000768170; AC1MCJZ0; CHEMBL548708; GTPL6404; cid_2745583; BDBM46991; HMS1669J02; SR-01000768170-4; SR-01000768170-3; SR-01000768170-2; 3-(4-chlorophenyl)-5-methyl-4-(2-tosylpyrazol-3-yl)isoxazole
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C20H16ClN3O3S
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| Canonical SMILES |
CC1=CC=C(C=C1)S(=O)(=O)N2C(=CC=N2)C3=C(ON=C3C4=CC=C(C=C4)Cl)C
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| InChI |
1S/C20H16ClN3O3S/c1-13-3-9-17(10-4-13)28(25,26)24-18(11-12-22-24)19-14(2)27-23-20(19)15-5-7-16(21)8-6-15/h3-12H,1-2H3
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| InChIKey |
WFFKVDICECGSHN-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Mucolipin-3 (TRPML3) | Target Info | Activator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6404). | |||
| REF 2 | Small molecule activators of TRPML3. Chem Biol. 2010 Feb 26;17(2):135-48. | |||
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