Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D04MAM
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| Former ID |
DNC004641
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| Drug Name |
Sulfamic acid chroman-2-ylmethyl ester
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| Synonyms |
CHEMBL180475; 835894-63-8; Sulfamic acid, (3,4-dihydro-2H-1-benzopyran-2-yl)methyl ester; Sulfamic acid chroman-2-ylmethyl ester; SCHEMBL5274616; CTK3D1605; DTXSID80463432; BDBM50163317; (3,4-dihydro-2H-chromen-2-yl)methyl sulfamate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H13NO4S
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| Canonical SMILES |
C1CC2=CC=CC=C2OC1COS(=O)(=O)N
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| InChI |
1S/C10H13NO4S/c11-16(12,13)14-7-9-6-5-8-3-1-2-4-10(8)15-9/h1-4,9H,5-7H2,(H2,11,12,13)
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| InChIKey |
OXNGFJDSVRPPCH-UHFFFAOYSA-N
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| CAS Number |
CAS 835894-63-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Collecting duct acid secretion | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| EGFR1 Signaling Pathway | ||||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | |||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| Reversible hydration of carbon dioxide | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Comparison of sulfamate and sulfamide groups for the inhibition of carbonic anhydrase-II by using topiramate as a structural platform. J Med Chem. 2005 Mar 24;48(6):1941-7. | |||
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