Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04LOR
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| Former ID |
DIB015859
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| Drug Name |
BMS-919373
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| Indication | Atrial fibrillation [ICD-11: BC81.3; ICD-10: I48] | Phase 2 | [1] | |
| Company |
Bristol-myers squibb
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| Structure |
 |
Download2D MOL |
||
| Formula |
C25H20N6O2S
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| Canonical SMILES |
C1=CC=C(C=C1)C2=C3C(=CC=C2)N=C(N=C3NCC4=CC=CC=N4)C5=CC(=CN=C5)S(=O)(=O)N
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| InChI |
1S/C25H20N6O2S/c26-34(32,33)20-13-18(14-27-16-20)24-30-22-11-6-10-21(17-7-2-1-3-8-17)23(22)25(31-24)29-15-19-9-4-5-12-28-19/h1-14,16H,15H2,(H2,26,32,33)(H,29,30,31)
|
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| InChIKey |
XGKULQQVQWCASY-UHFFFAOYSA-N
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| CAS Number |
CAS 1272353-82-8
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated potassium channel Kv1.5 (KCNA5) | Target Info | Inhibitor | [2] |
| Pathwhiz Pathway | Muscle/Heart Contraction | |||
| Reactome | Voltage gated Potassium channels | |||
| WikiPathways | Potassium Channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT02156076) A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation. U.S. National Institutes of Health. | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800035504) | |||
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