Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04JSE
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| Former ID |
DIB003008
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| Drug Name |
MK-7725
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| Synonyms |
BRS-3 agonists (obesity); BRS-3 agonists (obesity), Merck; Bombesin receptor subtype-3 agonists (obesity), Merck
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| Drug Type |
Small molecular drug
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| Indication | Obesity [ICD-11: 5B81; ICD-10: E66; ICD-9: 278] | Investigative | [1] | |
| Company |
Merck & Co Inc
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| Structure |
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Download2D MOL |
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| Formula |
C25H19F6N5O5S
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| Canonical SMILES |
CC(C)(C1=NC(=NO1)C2=C3C(=CC=C2)NC4=C(CN3S(=O)(=O)C5=CC=C(C=C5)OC(F)(F)F)C=CC(=N4)C(F)(F)F)O
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| InChI |
1S/C25H19F6N5O5S/c1-23(2,37)22-34-21(35-41-22)16-4-3-5-17-19(16)36(12-13-6-11-18(24(26,27)28)33-20(13)32-17)42(38,39)15-9-7-14(8-10-15)40-25(29,30)31/h3-11,37H,12H2,1-2H3,(H,32,33)
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| InChIKey |
WQQNCCUPGPFWOI-UHFFFAOYSA-N
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| CAS Number |
CAS 1034152-95-8
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bombesin-like receptor 3 (BRS3) | Target Info | Agonist | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8502). | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8502). | |||
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