Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D04JCN
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| Former ID |
DAP000069
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| Drug Name |
Pergolide
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| Synonyms |
Pergolida; Pergolidum; Permax; Pergolida [INN-Spanish]; Pergolide (INN); Pergolide [INN:BAN]; Pergolidum [INN-Latin]; Permax (TN); LY-127,809; (6aR,9R,10aR)-9-(Methylthiomethyl)-7-propyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline; (8beta)-8-[(methylsulfanyl)methyl]-6-propylergoline; (8beta)-8-[(methylthio)methyl]-6-propylergoline
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| Drug Type |
Small molecular drug
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| Indication | Parkinson disease [ICD-11: 8A00.0; ICD-9: 332] | Approved | [1], [2] | |
| Therapeutic Class |
Antiparkinson Agents
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| Company |
Valeant Pharmaceuticals
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| Structure |
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Download2D MOL |
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| Formula |
C19H26N2S
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| Canonical SMILES |
CCCN1CC(CC2C1CC3=CNC4=CC=CC2=C34)CSC
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| InChI |
1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3/t13-,16-,18-/m1/s1
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| InChIKey |
YEHCICAEULNIGD-MZMPZRCHSA-N
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| CAS Number |
CAS 66104-22-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9629, 7980280, 8180418, 11335617, 11360856, 11364541, 11367103, 11369665, 11372755, 11374547, 11377827, 11461828, 11466323, 11467443, 11485835, 11486185, 11489786, 11491403, 11492650, 11495461, 14825868, 14874447, 22390536, 24263009, 26754330, 26754331, 34712767, 46507604, 47588942, 47588943, 47662223, 47736415, 47736416, 47810696, 47810697, 47885355, 48110404, 48259176, 48416397, 48484161, 49698421, 49965528, 50109822, 50586184, 57288804, 57313147, 85788351, 85789354, 90341767, 92308734
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| ChEBI ID |
CHEBI:63617
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| ADReCS Drug ID | BADD_D01735 ; BADD_D01736 | |||
| SuperDrug ATC ID |
N04BC02
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| SuperDrug CAS ID |
cas=066104221
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 48). | |||
| REF 2 | Novel pharmacological targets for the treatment of Parkinson's disease. Nat Rev Drug Discov. 2006 Oct;5(10):845-54. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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