Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D04HMD
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| Former ID |
DNC000698
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| Drug Name |
Glyphosate
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| Synonyms |
glyphosate; 1071-83-6; N-(Phosphonomethyl)glycine; Glyphosphate; Roundup; Glycine, N-(phosphonomethyl)-; N-Phosphonomethyl-glycine; 2-(phosphonomethylamino)acetic acid; Silglif; Pondmaster; Roundup Max; N-Phosphonomethylglycine; N-Phosphomethylglycine; Caswell No. 661A; MON 2139; C3H8NO5P; N-(Phosphonomethyl) Glycine; NSC151063; Glialka; Phosphonomethyliminoacetic acid; Mon 6000; Glyphosate [ANSI:BSI:ISO]; UNII-4632WW1X5A; CCRIS 1587; CP 67573; HSDB 3432; XDDAORKBJWWYJS-UHFFFAOYSA-N; EINECS 213-997-4; 2-((Phosphonomethyl)amino)acetic
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| Drug Type |
Small molecular drug
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| Indication | Malaria [ICD-11: 1F40-1F45; ICD-10: B50-B64, B54] | Investigative | [1], [2] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C3H8NO5P
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| Canonical SMILES |
C(C(=O)O)NCP(=O)(O)O
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| InChI |
1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)
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| InChIKey |
XDDAORKBJWWYJS-UHFFFAOYSA-N
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| CAS Number |
CAS 1071-83-6
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| PubChem Compound ID | ||||
| PubChem Substance ID |
4843, 431953, 641147, 820444, 831699, 4253856, 7351417, 8140335, 8144466, 8152220, 10317452, 10319579, 11341749, 11361932, 11364792, 11367354, 11369916, 11371996, 11374256, 11378082, 11405455, 11457427, 11459511, 11485370, 11487334, 11489663, 11490655, 11492494, 11495681, 14716439, 14716441, 15321860, 24860496, 24869040, 24887470, 24895166, 24899043, 26613387, 26651956, 26679363, 26737410, 26737413, 26747743, 26747744, 29222628, 33618611, 46394186, 46394187, 47515457, 48259398
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| ChEBI ID |
CHEBI:27744
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Phosphoshikimate1-carboxyvinyltransferase (Bact aroA) | Target Info | Inhibitor | [3] |
| Plasmodium Enopyruvyl shikimate phosphate synthase (Malaria ESPS) | Target Info | Inhibitor | [1], [2] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The apicoplast as an antimalarial drug target. Drug Resist Updat. 2001 Jun;4(3):145-51. | |||
| REF 2 | Novel molecular targets for antimalarial drug development. Chem Biol Drug Des. 2008 Apr;71(4):287-97. | |||
| REF 3 | Novel molecular targets for antimalarial chemotherapy. Int J Antimicrob Agents. 2007 Jul;30(1):4-10. | |||
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