Drug Information
Drug General Information | Top | |||
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Drug ID |
D04GWY
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Former ID |
DIB001152
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Drug Name |
Telinavir
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Synonyms |
SC-52151
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Drug Type |
Small molecular drug
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Indication | Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 279.3] | Discontinued in Phase 2 | [1] | |
Company |
GD Searle & Co
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Structure |
Download2D MOL |
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Formula |
C33H44N6O5
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Canonical SMILES |
CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)C(CC(=O)N)NC(=O)C2=NC3=CC=CC=C3C=C2)O)C(=O)NC(C)(C)C
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InChI |
1S/C33H44N6O5/c1-21(2)19-39(32(44)38-33(3,4)5)20-28(40)26(17-22-11-7-6-8-12-22)36-31(43)27(18-29(34)41)37-30(42)25-16-15-23-13-9-10-14-24(23)35-25/h6-16,21,26-28,40H,17-20H2,1-5H3,(H2,34,41)(H,36,43)(H,37,42)(H,38,44)/t26-,27-,28+/m0/s1
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InChIKey |
ZILOOGIOHVCEKS-HZFUHODCSA-N
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CAS Number |
CAS 143224-34-4
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Human immunodeficiency virus Protease (HIV PR) | Target Info | Inhibitor | [2] |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003330) | |||
REF 2 | Improvement of bioavailability of the HIV protease inhibitor SC-52151 in the beagle dog by coadministration of the CYP3A4 inhibitor, ketoconazole. Xenobiotica. 1997 May;27(5):489-97. |
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