Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04DSD
|
|||
| Former ID |
DIB000746
|
|||
| Drug Name |
TEI-5178
|
|||
| Synonyms |
[1R-[1alpha,2beta(1E,3S*),3alpha]]-6-[[2-(3-Cyclohexyl-3-hydroxy-1-propenyl)-3-hydroxy-5-oxocyclopentyl]thio]hexanoic acid methyl ester; 15-Cyclohexyl-16,17,18,19,20-pentanor-7-thiaprostaglandin E1 methyl ester
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Nephritis [ICD-11: GB40] | Phase 1 | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C21H34O5S
|
|||
| Canonical SMILES |
COC(=O)CCCCCSC1C(C(CC1=O)O)C=CC(C2CCCCC2)O
|
|||
| InChI |
1S/C21H34O5S/c1-26-20(25)10-6-3-7-13-27-21-16(18(23)14-19(21)24)11-12-17(22)15-8-4-2-5-9-15/h11-12,15-18,21-23H,2-10,13-14H2,1H3/b12-11+/t16-,17?,18+,21+/m0/s1
|
|||
| InChIKey |
QNKCYDKEIICCMC-RJOSLXAASA-N
|
|||
| CAS Number |
CAS 83009-96-5
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Antinephritic effects of PGE1 and thiaprostaglandin E1, TEI-5178 and TEI-6122, on crescentic-type anti-GBM nephritis in rats. Jpn J Pharmacol. 1989 Dec;51(4):521-30. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.