Drug Information
Drug General Information | Top | |||
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Drug ID |
D04CDO
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Former ID |
DNCL002103
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Drug Name |
TAS-102
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Synonyms |
Tipiracil / Trifluridine; Viroptic mixture with 5-CIMU; TAS 102; EX-A1755; Tipiracil hydrochloride / Trifluridine; Tipiracil hydrochloride mixture with Trifluridine; 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione compound with 5-chloro-6-((2-iminopyrrolidin-1-yl)methyl)pyrimidine-2,4(1H,3H)-dione (1:1) hydrochloride; Thymidine, alpha,alpha,alpha-trifluoro-, mixt. with 5-chloro-6-((2-imino-1-pyrrolidinyl)methyl)-2,4(1H,3H)-pyrimidinedione monohydro
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Drug Type |
Small molecular drug
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Indication | Colorectal cancer [ICD-11: 2B91.Z] | Phase 3 | [1] | |
Company |
Taiho Pharma U.S.A.
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Structure |
Download2D MOL |
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Formula |
C19H23Cl2F3N6O7
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Canonical SMILES |
C1CC(=N)N(C1)CC2=C(C(=O)NC(=O)N2)Cl.C1C(C(OC1N2C=C(C(=O)NC2=O)C(F)(F)F)CO)O.Cl
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InChI |
1S/C10H11F3N2O5.C9H11ClN4O2.ClH/c11-10(12,13)4-2-15(9(19)14-8(4)18)7-1-5(17)6(3-16)20-7;10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11;/h2,5-7,16-17H,1,3H2,(H,14,18,19);11H,1-4H2,(H2,12,13,15,16);1H/t5-,6+,7+;;/m0../s1
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InChIKey |
PLIXOHWIPDGJEI-OJSHLMAWSA-N
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CAS Number |
CAS 733030-01-8
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PubChem Compound ID | ||||
PubChem Substance ID |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT01955837) Study of TAS-102 in Patients With Metastatic Colorectal Cancer in Asia. U.S. National Institutes of Health. |
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