Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04BDL
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| Former ID |
DIB019465
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| Drug Name |
PMID22123324C38
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| Synonyms |
GTPL7757
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C30H34N4O
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| Canonical SMILES |
CCCNC1CC2(CCN(CC2)CC3=CC4=C(C=C3)N(C5=CC=CC=C54)C(=O)N)C6=CC=CC=C16
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| InChI |
1S/C30H34N4O/c1-2-15-32-26-19-30(25-9-5-3-8-23(25)26)13-16-33(17-14-30)20-21-11-12-28-24(18-21)22-7-4-6-10-27(22)34(28)29(31)35/h3-12,18,26,32H,2,13-17,19-20H2,1H3,(H2,31,35)/t26-/m1/s1
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| InChIKey |
LMNFAMWQPPUUNJ-AREMUKBSSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Melanin-concentrating hormone receptor 2 (MCHR2) | Target Info | Antagonist | [1] |
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| G alpha (i) signalling events | ||||
| WikiPathways | Gastrin-CREB signalling pathway via PKC and MAPK | |||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery and characterization of a potent and selective antagonist of melanin-concentrating hormone receptor 2. Bioorg Med Chem Lett. 2012 Jan 1;22(1):363-6. | |||
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