Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03YMX
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| Former ID |
DNC005188
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| Drug Name |
3,4,6-Tribromo-2-(2,4-dibromo-phenoxy)-phenol
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| Synonyms |
CHEMBL186098; 6-hydroxy-2,2',3,4',5-pentabromodiphenyl ether; 3,4,6-Tribromo-2-(2,4-dibromo-phenoxy)-phenol; ZINC95606620; BDBM50150782; 497069-29-1; 2-(2,4-Dibromophenoxy)-3,4,6-tribromophenol
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H5Br5O2
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| Canonical SMILES |
C1=CC(=C(C=C1Br)Br)OC2=C(C(=CC(=C2Br)Br)Br)O
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| InChI |
1S/C12H5Br5O2/c13-5-1-2-9(6(14)3-5)19-12-10(17)7(15)4-8(16)11(12)18/h1-4,18H
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| InChIKey |
FAGFPLJEMPQMRV-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arachidonate 12-lipoxygenase (12-LOX) | Target Info | Inhibitor | [1] |
| Arachidonate 15-lipoxygenase (15-LOX) | Target Info | Inhibitor | [1] | |
| BioCyc | Lipoxin biosynthesis | |||
| Resolvin D biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Linoleic acid metabolism | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| Pathway Interaction Database | IL4-mediated signaling events | |||
| WikiPathways | Arachidonic acid metabolism | |||
| Eicosanoid Synthesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase. J Med Chem. 2004 Jul 29;47(16):4060-5. | |||
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